Michal Česnek

Všechny publikace

Nejnovější publikace

Discovery of a potent and selective human AC2 inhibitor based on 7-deazapurine analogues of adefovir

P. Kraina M. Česnek E. Tloušťová H. Mertlíková-Kaiserová C. J. Fulton E. K. Davidson B. P. Smith V. J. Watts Z. Janeba

Bioorganic & Medicinal Chemistry 95: 117508 (2023)

Stereo-Defined Acyclic Nucleoside Phosphonates are Selective and Potent Inhibitors of Parasite 6-Oxopurine Phosphoribosyltransferases

T. Klejch D. T. Keough G. King E. Doleželová M. Česnek M. Buděšínský A. Zíková Z. Janeba L. W. Guddat D. Hocková

Journal of Medicinal Chemistry 65 (5): 4030–4057 (2022)

Halogen-Dance-Based Synthesis of Phosphonomethoxyethyl (PME) Substituted 2-Aminothiazoles as Potent Inhibitors of Bacterial Adenylate Cyclases

M. Česnek M. Šafránek M. Dračínský E. Tloušťová H. Mertlíková-Kaiserová M. P. Hayes V. J. Watts Z. Janeba

ChemMedChem 17 (1): e202100568 (2022)

Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases

P. Břehová E. Chaloupecká M. Česnek J. Skácel M. Dračínský E. Tloušťová H. Mertlíková-Kaiserová M. P. Soto-Velasquez V. J. Watts Z. Janeba

European Journal of Medicinal Chemistry 222: 113581 (2021)